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EB病毒潜伏膜蛋白1在鼻咽癌形成中的作用 被引量：3

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摘要 EB病毒潜伏感染在鼻咽癌的形成中起着重要的作用。现综述近年来研究EB病毒潜伏膜蛋白 1在鼻咽癌形成作用中的进展情况 ,并着重介绍其对细胞信号传导通路、血管生成及转移等的影响。
作者 向燕群 闵华庆
机构地区 中山大学肿瘤防治中心鼻咽癌科
出处 《国外医学（肿瘤学分册）》 2004年第1期49-52,共4页 Foreign Medical Sciences (Cancer Section)
关键词 EB病毒 潜伏膜蛋白1 鼻咽癌 细胞凋亡
分类号 R739.63 [医药卫生—肿瘤]
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参考文献20

  • 1Fielding CA, Sandvej K, Mehl A, et al. Epstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways. J Virol,2001,75(19) :9129-9141.
  • 2Kawanishi M. The Epstein-Barr virus latent membrane protein 1( LMP- 1 ) enhances TNFalpha-induced apop*osis of imestinc 407 epithelial cells: The role of LMP-1 C-terminal activation regions 1 and 2. Virology., 2000, 270(2): 258-266.
  • 3Teramoto N, Maeda A, Kobayashi K, et al. Epstein-Barr virus infection to Epstein-Barr virus-negative nasopharyngeal carcinonm cell line TW03 enhances its tumorigenicity. Lab Invest, 2000,80 ( 3 ) ;303-312.
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  • 6Ardila-Osorio H, Clausse B, Mishal Z, et al. Evidence of LMP1-TRAFB interactions in glycosphingolipid-rich complexes of lymphoblastoid and nasopharyngeal carcinoma cells. Int J Cancer, 1999,81(4) : 645-649.
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同被引文献36

  • 1汤建国,李旋,陈萍.Expression of matrix metalIoproteinase-9 in nasopharyngeal carcinoma and association with Epstein-Barr virus infection[J].Journal of Zhejiang University Science,2004,5(10):1304-1312. 被引量：6
  • 2刘加强,杨富生.关于基质金属蛋白酶9(MMP-9)的最新进展[J].牙体牙髓牙周病学杂志,2005,15(3):168-171. 被引量：22
  • 3刘雄,李湘平,彭英,李刚,张宝,李晓华,周立辉.腺相关病毒介导RNA干扰抑制EB病毒潜伏膜蛋白1基因表达[J].中国耳鼻咽喉头颈外科,2006,13(11):762-765. 被引量：3
  • 4Hu LF, Chen F, Zheng X, et al. Clonability and tumorigenicity of human epithelial cells expressing the EBV encoded membrane protein LMP1 [J]. Oncogene, 1993, 8: 1575-83.
  • 5Teo PML, Chan ATC. Treatment strategy and clinical experience [J]. Semin Cancer Biol, 2002, 12: 497-504.
  • 6Ma BBY, Chan ATC. Recent perspectives in the role of chemotherapy in the management of advanced nasopharyageal carcinoma[J]. Cancer, 2005, 103:22-31.
  • 7Epstein-barr virus (group 1). International agency for reasearch on cancer (IARC)[J]. Summ Eval, 1997, 70: 47.
  • 8Wang D, Liebowitz D, Kieff E. An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells[J]. Cell, 1985, 43(3 Pt 2): 831-40.
  • 9Pathmanathan RU, Prasad U, Sadler R, et al. Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinoma [J]. N Engl J Med, 1995, 333(11): 693-8.
  • 10Horikawa T, Yoshizaki T, Sheen TS, et al, Association of latent membrane protein 1 and matrix metalloproteinase 9 with metastasis in nasopharyngeal carcinoma[ J ]. Cancer, 2000, 89(4): 715-23.

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国外医学（肿瘤学分册）
2004年 第1期

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