期刊文献+

细胞内铜途径:铜伴侣蛋白的作用 被引量:3

Intracellular Copper Routing:The Role of Copper Chaperones
下载PDF
导出
摘要 铜是生物体必需的微量元素.目前发现,体内铜平衡机制是蛋白质介导的,它将细胞内的铜传递给靶蛋白.这一途径是通过新的蛋白质家族———铜伴侣蛋白实现的.铜伴侣蛋白对细胞内铜途径有重要作用.介绍了金属伴侣蛋白的功能、结构特点及铜伴侣蛋白的作用. Copper is required by all living systems. Cells have a variety of mechanisms to deal with this essential, toxic trace element. A recently discovered homeostatic mechanism is the protein-mediated, intracellular delivery of copper to target proteins. Copper chaperones play an important role in intracellular copper routing. The function and structure of metallochaperone and copper chaperones were summarized.
作者 郭彤 许梓荣
出处 《科技通报》 北大核心 2004年第1期73-76,共4页 Bulletin of Science and Technology
关键词 微量元素 铜伴侣蛋白 细胞内传递 传递途径 平衡机制 copper chaperones intracellular delivery routing
  • 相关文献

参考文献29

  • 1Halliwell B, Gutteridge J M. The importance of free radicals and catalytic metal ions in human disease[J]. Mol Asp Med, 1995,8:89- 193.
  • 2Laskey R A, Honda B. Molecular chaperones in cellular protein folding. Nature, 1978,275:416 - 420.
  • 3Ellis R J. Do molecular chaperones have to be proteins? Nature, 1987,328 : 378 - 379.
  • 4Odermatt A. Primary structure of two P-type ATPases involved in copper homeostasis in Enterococcus hirae [ J]. Biol Chem, 1993,268: 12775 - 12779.
  • 5Lutsenko S, Kaplan J H. Organization of P-type ATPases: significance of structural diversity[J]. Biochemistry, 1995,34: 15608 - 15613.
  • 6Solioz M, Vulpe C. CPx-type ATPase a class of P-type ATPases that pump heavy metals[J]. Trends Biochem Sci, 1996,21:237 - 241.
  • 7Sohoz M, Odermatt A. Copper and silver transport by copB-ATPase in membrane vesicles of Enterococcus hirae [J]. Biol Chem, 1995,270: 9217 - 9221.
  • 8Cobine P.The Enterococcus hirae copper chaperone CopZ delivers Cu ( Ⅰ ) to the CooY reoressor[J] .FEBS Lett, 1999,445:27- 30.
  • 9Klomp L W J. Identification and functional expression of HAH1, a novel human gene involve in copper homeostasis [ J ]. Biol Chem, 1997,272:9221 - 9226.
  • 10Solioz M, Vulpe C. CPx-type ATPase - a class of P-type ATPases that pump heavy metal[J]. Trends Biochem Sci, 1996,21:237-241.

同被引文献33

  • 1全先庆,张洪涛,单雷,毕玉平.植物金属硫蛋白及其重金属解毒机制研究进展[J].遗传,2006,28(3):375-382. 被引量:42
  • 2陆修闽,刘庆,徐娟,黄新忠,金光,卢新坤,陈小明.红肉蜜柚果肉红色色素鉴定[J].亚热带植物科学,2006,35(1):39-41. 被引量:17
  • 3黄新忠,陆修闽,卢新坤,陈小明,林海清,林金山,蔡盛华.早熟优质蜜柚新品种——红肉蜜柚的选育[J].果树学报,2007,24(1):123-124. 被引量:31
  • 4Bevan M, Baneroft I, Bent E, Love K, Goodman H, Dean C, Bergkamp R, Dirkse W, Van Staveren M, Stiekema W. 1998. Analysis of 1.9 Mb of contiguous sequences from chromosome 4 ofArabidopsis thaliana. Nature, 391 : 485 - 488.
  • 5Castellarin S D, Gambetta G A, Wada H, Shackel K A, Matthews M A. 2011. Fruit ripening in Fitis vinifera: Spatiotemporal relationships among turgor, sugar accumulation, and anthocyanin biosynthesis. Journal of Experimental Botany, 62 (12): 4345 - 4354.
  • 6Diatchenko L, Lau Y F, Campbell A E 1996. Suppression Subtractive hybridization: A method for generating differentially regulated or tissue-specific cDNA probes and libraries. Proc Natl Sci USA, 93 (12):6025 - 6030.
  • 7Goulao L F, Oliveira C M. 2008. Cell wall modifications during fruit ripening: When a fiuit is not the fruit. Trends Food Sci Tech, 19 (1): 4 - 25.
  • 8GuillaumieS, FouquetR, KappelC, Camps C, TerrierN, MoncombleD, DunlevyJD, Davies C, Boss PK, DelrotS. 2011. Transcriptional analysis of late ripening stages of grapevine berry. BMC Plant Biology, 11 : 165.
  • 9Johansson M, Hammargren J, Uppsall E, MacKenzie A, Knorpp C. 2008. The activities ofnucleoside diphosphate kinase and adenylate kinase are influenced by their interaction. Plant Science, 174 (2): 192 - 199.
  • 10Li Juan, Zhang Pan-pan, Chen Jie-zhong, Yao Qing, Jiang Yue-ming. 2009. Cellular wall metabolism in citrus fruit pericarp and its relation to creasing fruit rate. Scientia Horticultulae, 122:45 - 50.

引证文献3

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部