维持性血液透析患者TTV病毒医院感染因素分析

Risk factors of transfusion transmitted virus nosocomial infection in patients with maintenance hemodialysis

目的 探讨维持性血液透析患者输血传播性病毒 (TTV)感染情况 ,对其发生医院感染的危险因素进行分析。方法 采用PCR技术检测 86例维持性血液透析患者TTV感染情况 ,并对感染组和非感染组间是否有输血史、输血次数、透析时间 ,透析器重复使用情况进行对比分析。结果 维持性血液透析患者TTV感染率为 5 3 .49% (4 6/86) ,其原因与输血史有关系 (P <0 .0 1) ,也与输血次数、透析时间、透析器重复使用次数有关 (P均 <0 .0 5 )。结论 维持性血液透析患者存在严重的TTV感染 ,避免接受输血与重复使用血液透析器或者减少其次数 ,加强血液透析机的消毒 。

Objective To investigate the transfusion transmitted virus (TTV) infection in patients with maintenance hemodialysis, and analyzed the risk factors of nosocomial infection.Methods The TTV infection condition was detected in 86 patients with maintenance hemodialysis by using a PCR technique. The comparison of blood tranfusion history, times of blood tranfusion, duration of dialysis and the times of the blood dialysis aparatus reused between the infected group and the noninfectious group had been undertaken and analyzed. Results The TTV infected rate in patients with maintenance dialysis was 53.49% (46/89). Data analysis showed that the TTV infection was associated with blood transfusion history (P<0.01), as well as with the times of blood transfusion, duration on hemodialysis, and the times of blood dialysis aparatus resused, all the P values were <0.05. Conclusion TTV infection is seriously in patients with maintenance hemodialysis. To avoid blood transfusion and limit the use of the blood dialysis aparatus and strengthen the sterilization for the dialysis aparatus are of great importance in prevention and decreasing the TTV nosocomial infection in patients with maintenance hemodialysis.