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RA患者抗天然II型胶原抗体与ESR、CRP、AAG之间的关系 被引量:1

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摘要 为探讨抗天然II型胶原抗体 (抗NatII)在类风湿性关节炎 (RA )疾病活动中的意义。采用ELISA检测抗NatIIIgG ,用BNprospec特定蛋白分析仪检测C 反应蛋白 (CRP )和α1 酸性糖蛋白 (AAG ) ,Electa血沉仪测定红细胞沉降率 (ESR )。结果 6 0例RA患者血清抗NatIIIgG水平与ESR和血清CRP、AAG含量呈正相关 (相关系数r分别为 0 4 0 2、 0 2 6 8和 0 382 ) ,其中2 3例抗NatIIIgG阳性患者的ESR、CRP、AAG均显著高于抗NatIIIgG阴性者 (P <0 0 1)。抗NatIIIgG可作为RA疾病活动性指标之一。
出处 《上海免疫学杂志》 CSCD 北大核心 2003年第6期421-421,426,共2页 Shanghai Journal of Immunology
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  • 1Darzynkiewicz Z, Gloria J, Li X, et al. Cytometry in cell microbiology:analysis of apoptosis and accidental cell death (necrosis)[J]. Cytometry, 1997,27 : 1.
  • 2Stuary JM, Cremer MA, Townes AS, et al. Type II collagen induced arthritis in rats. Passive transfer with serum and evidence that IgG anticollagen antibodies can cause arthritis[J]. J Exp Med, 1982,155 : 1.
  • 3Kuniak T, Karen AH, Robert AR, et al. Induction of arthritis with monoclonal antibodies to collagen[J]. J Immunol, 1992,148:2103.
  • 4Cook AD, Rowley MJ, Maekey IR, et al. Antibodies to type II collagen in early rheumatoid arthritis[J]. Arthritis Rheum, 1996,30:1720.
  • 5林星,余家族,陈健,郑斌生,李倩.类风湿关节炎实验室诊断进展[J].现代诊断与治疗,2002,13(1):27-29. 被引量:13

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  • 1周强,李霞,李茹,郑伟毅,栗占国.类风湿关节炎患者Ⅱ型胶原特异性T细胞增殖及抗体生成与HLA-DR4的关系[J].中华医学杂志,2005,85(6):370-373. 被引量:4
  • 2Myers LK,Tang B,Rosloniec EF,et al.Characterization of a peptide analog of determinant of type II collagen that suppresses collagen-induced arthritis[J].J Immunol,1998,161:3589-3595.
  • 3Cheng YZ,Zhou Q,Li ZG.The inhibitory effect of altered collagen II peptide on HLA-DRB1-restricted T-cell activation[J].Scand J Immunol,2005,61:260-265.
  • 4Dayan M,Sthoeger Z,Neiman A,et al.Immunomodulation by a dual altered peptide ligand of autoreactive responses to the acetylcholine receptor of peripheral blood lymphocytes of patients with myasthenia gravis[J].Hum Immunol,2004,65:571-577.
  • 5Andersson EC,Hansen BE,Jacobsen H,et al.Definition of MHC and T cell receptor contacts in the HLA-DR4 restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice[J].Proc Natl Acad Sci USA,1998,95:7574-7579.
  • 6Fugger L,Rothbard JB,Sonderstrup-McDevitt G.Specificity of an HLA-DRB1*0401-restricted T cell response to type II collagen[J].Eur J Immunol,1996,26:928-933.
  • 7Myers LK,Sakurai Y,Tang B,et al.Peptide-induced suppression of collagen-induced arthritis in HLA-DR1 transgenic mice[J].Arthritis Rheum,2002,46:3369-3377.
  • 8Zhou Q,Cheng YZ,Li ZG,et al.Inhibition of T cell activation with HLA-DR1/DR4 restricted non-T-cell stimulation peptides[J].Human Immunol,2003,64:857-865.
  • 9张冬青,李宁丽,余奇文,马安伦,张勇,周光炎,JackPAntel,YufenQin.多发性硬化症患者APL特异性T细胞系免疫生物学特性分析[J].上海免疫学杂志,2000,20(4):214-216. 被引量:1
  • 10周强,程永静,栗占国,周卫红,吕厚山.人类白细胞抗原-DRβ1特异性低T细胞反应性肽对T细胞激活的抑制作用[J].中华医学杂志,2003,83(17):1505-1509. 被引量:2

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