“治疣汤”治疗尖锐湿疣的临床疗效及IL-2水平的变化

Effect of "Curing Verruca Decoction" on Condyloma Acuminatum in Clinical Efficiency and IL-2 Level

目的探讨“治疣汤“治疗尖锐湿疣的临床疗效及免疫调节作用。方法将 88例患者分为中药组 (激光加“治疣汤”)和西药组 (激光加病毒唑和多种维生素 ) ,观察其临床疗效并采用双抗夹心法(ELISA)检测治疗前、后血清中白介素IL -2水平的变化。结果①中药组临床疗效明显优于西药组 (P<0 .0 1 ) ;②中药组治疗后血清IL -2水平明显升高 (P <0 .0 5 ) ,西药组治疗前后无明显差异 (P >0 .0 5 )。结论中药治疣汤是治疗尖锐湿疣的有效药物 ,它不仅具有抗病毒的作用 ,而且具有免疫调节作用 。

Objective To study the clinical efficiency and effect of immune-regulation of 'curing verruca decoction' (CVD) in treating the condyloma acuminatum (CA).Methods Eighty-eight patients with CA were randomly divided into two groups:Chinese traditional medicine group (administration with CVD after laser-resection) and western medicine group (administration with virazole and vitamins after laser-resection).Before and after treatment,the change in IL-2 level of the serum was assayed with ELISA and the chinical efficiency was observed.Results ①The clinical efficiency in CVD group was obviously better than that in virazole group (P<0.01),②The improvement of the IL-2 level in the serum was significant after treatment in CVD group (P<0.05),while in the virazole group it was not significant(P>0.05).Conclusion Chinese traditional medicine 'Curing verruca decoction' is an effective drug on CA,not only effective in the antivirus but also effective in immune regulation,and it can lessen the recurence of the Condyloma Acuminatum.