摘要
Objective To inviestigate the expression of gall bladder cancer and its relationship with eaneeration. Methods Immunohistoehemistry techniques are used to detect the expression of p53 protein in 36 eases of gall bladder cancer and 23 adenoma. Results p53 protein were founded positive in 19 cases (52.78%) of gall blodder cancer, in 5 cases (21.74%) of adenoma. Conclusion There is close relationship between the over expression and the cancemtion of gall bladder, p53 gene mutation and over expression are in the early stage of gall bladder cancer, and play an important role in the cancemtion of adenoma.
