乳泉颗粒对实验性产后泌乳不足大鼠的影响

The Effect of Ruquan Granules on Experimental Dysgalactia Rats

目的:验证乳泉颗粒的主要药理作用。方法:以己烯雌酚造成大鼠产后泌乳不足模型。结果:对实验性产后泌乳不足的Wistar大鼠灌胃给予乳泉颗粒10d,可使母鼠泌乳量明显增多,仔鼠体重、身长增长加速,且母鼠的血清催乳素分泌水平有所提高。显微镜观察结果表明,实验性泌乳不足母鼠的乳腺大部分组织腺体萎缩,小叶间结缔组织增多,而乳泉颗粒给药组可见腺体扩张、增多,小叶间结缔组织亦显著减少。结论:乳泉颗粒具有显著的增加泌乳量的作用。

Objective:To validate the mainly pharmacological effect of Ruquan Granules. Methods:Causing dysgalactia of rats by injecting diethylstilbestrol injection. Results:Ruquan Granules has the enhancement for lactation, the weight and the stature of pups. It could increase the concentration of serumal prolactin. Histopathologic evaluation revealed that most glands of mammary gland atrophy and the interlobular connective tissue were increased by injecting diethylstilbestrol injection. Ruquan Granules could mend these symptoms. Conclusion:Ruquan Granules has a remarkable effect of enhancing lactation.