尿毒症患者左室重构及相关因素分析

The analysis of left ventricular structure changes and related factors of patients with uremia

目的探讨尿毒症患者左室重构的相关因素。方法对120例尿毒症患者的临床资料及心脏超声的检测结果进行了统计学分析。结果左室肥厚、扩大为临床中普遍存在的病理结构变化。收缩压、舒张压与左室肥厚、扩大呈明显正相关(P<0.05),而血红蛋白浓度与左室肥厚、扩大呈明显负相关(P<0.05)。血清白蛋白浓度仅与左室扩大呈负相关(P<0.05)。同时左室扩大与左房、右房、右室的扩大也存在明显正相关(P<0.05),左室肥厚与此无明显相关性(P>0.05)。结论血压越高、贫血越重,意味着左室肥厚、扩大越明显。营养不良可能加重左室扩大。左室结构的变化与左房、右房、右室的结构变化呈一致性。

Objective To realize the effect of related factors on left ventricular structure changes of patients with uremia.Method The collecting clinic data in 120 patients with uremia were statistically analysed.Result Left ventricular hypertrophy and dilation were common changes of pathological structure in clinic.The systolic pressure and diastolic pressure was positively related with left ventricular hyper-trophy and dilation, but the hemoglobin level was negatively related with left ventricular hypertrophy and dilation. Only the serum albumin level was negatively related with left ventricular dilation. And then left ventricular dilation was positively related with left atrium, right atrium and right ventricular dilation, but left ventricular hypertrophy was not related with above factors.Conclusion The higher hypertension and the worse anemia mean more obvious left ventricular hypertrophy and dilation. Malnutrition may make left ventricular dilation heavier. The left ventricular structure changes have consistence with the left atrium, the right atrium and the right ventricular dilation structure changes.