思密达预防窒息新生儿上消化道出血的疗效分析

Clinical analysis to prevent the upper gastro-enteric haemorrhage of asphyxic newborn infants treated with smecta

目的:探讨早期鼻饲思密达预防窒息新生儿上消化道出血的有效性和安全性。方法:选择100例窒息新生儿,其中随机选择50例作为预防组于窒息6h内鼻饲思密达,观察上消化道出血的发生率,50例作为对照组。结果:轻度窒息新生儿预防组和对照组上消化道出血的发生率分别为12.5%和31.4%,两者之间差异有显著性(P<0.05),重度窒息新生儿两组上消化道出血发生率分别为33.3%和86.6%,两者之间差异也有显著性(P<0.05)。结论:窒息新生儿早期鼻饲思密达能够有效的安全的降低上消化道出血的发生率,增加抢救成功率,减少禁食时间,减少使用静脉营养的次数,减轻患者负担。

Objective: To research the effects and safety of the preventive gastro-enteric haemorrhage of asphysic newborn infants treated with nasol tube fed smecta at their early stage. Methods: 50 cases of asphyxic newborn infants were treated by means of feeding smecta after 6 hours and other 50 cases in asphyxic as control group to observe its morbility of upper gastro-enteric haemorrhage. Results: Incidences of mild cases of asphyxic newborn infants with gastro-enteric haemorrhage were 12.5% and 31.4% in treated and control groups respectively, The difference was significant ( P < 0.05), The incidences of severe caseswere 33.3% and 86.6% respectively (P < 0.05). Conclusion: Early feeding nasol tube smecta in asphyxic newborn infans can lower the incidence of gastro-enteric haemorrhage, it has good effects and safty, in the same time it increase the rate of recovery, shorten the time of pereteral neutritions and lower the economic expenditure.