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肾大部切除制作慢性肾衰大鼠模型 被引量:7

Chronic Renal Failure Rat Models Made with Great Part Nephrectomy
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摘要 目的:总结肾大部切除术中意的问题。方法:比较大鼠肾脏大部切除的两中术式。结果:腹部正中纵切口的 感染率26.7%、死亡率13.3%,脊背部切口无一感染、死亡(P<0.01)。结论:肾大部切除术简便易行;脊背部切口是 值得推荐的一种肾大部切除术式。 Objective:To evaluate a modified operation technique with the chronic renal failure rats by great part nephrectomy. Methods :The effect and safety were compared between the two operative techniques in rats great part nephrectomy. Results: Infectious rate incised in rats in abdomen center was 26.7%, mortality rate of it was 13.3% . None of the rats incised in back were infected or dead ( P < 0.01) . Conclusion; Great part nephrectomy with chronic renal failure rat models is easy to carry out, the back incision is the more excellent nephrectomy operative technique.
出处 《医学理论与实践》 2003年第12期1367-1368,共2页 The Journal of Medical Theory and Practice
关键词 肾大部切除术 慢性肾功能衰竭 动物模型 切口感染 脊背部切口 腹部正中纵切口 Great part nephrectomy,Surgery methods, Chronic renal failure, Rats
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  • 2Gretz N, Floege J, Sugenoya Y, et al Nutritional treatment of CRF[J]. AM J Nephrol,1989,61,147-150.
  • 3Stemer G, Wennberg A. Partial nephrectomy and chronic renal failure, the "adult" rat model[J]. Gontr Nephrol,1988, 60:39-40.
  • 4Ritz E, Furst P, Yoshimura A. The role of the parathroid glands in the uremic syndrome[J],Am J Kidney Dis,1995,26: (5):808-811.

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