鄱阳湖血吸虫病重疫区居民连续6年吡喹酮化疗依从性研究

Compliance Study on Mass Chemotherapy with Praziquantel in Schistosomiasis Hyper-endemic Area of Poyang Lake Region for Successive 6 years

目的 探讨血吸虫病重疫区居民连续 6年吡喹酮全民化疗的依从性及其影响因素。方法 居民粪检和现场问卷调查。结果 1 992～ 1 997年实际化疗覆盖率分别为 63 .84%、67.1 9%、69.44%、62 .63 %、5 7.1 9%和73 .98% ,只有 2 9.0 5 %的居民参加全程化疗。未全程化疗居民中 ,42 .86%担心吡喹酮的副作用 ,2 7.72 %自认为未感染血吸虫不必服药 ,1 8.98%抱怨化疗收费 ,1 0 .45 %无理拒服。结论 此疫区人群每年实际化疗覆盖率均未达目标要求。建议采用适时化疗和健康教育提高居民化疗依从性。

Objective To explore the compliance and impact factors in mass chemotherapy with praziquantel among residents in schistosomiasis hyper endemic area of Poyang Lake region from 1992 to 1997. Method Questionaire investigation and stool examination were adopted. Results During 1992~1997, the coverage rates of mass chemotherapy among residents were 63.84%, 67.19%, 69.44%, 62.63%, 57.19%, and 73.98% respectively. Only 29.05% (192/661) of the residents took the chemotherapy once a year for successive 6 years. 70.95%(469/661) residents didn't take the chemotherapy every year in which 42.85% worried about the side effect of praziquantel, 27.72% thought that they didn't need to be treated because they didn't exposure in contaminated water, 18.98% complained the charge of the drug, and 10.45% rejected to have the drug without any reason. Conclusion The coverage rate of mass chemotherapy didn't reached the objective of the control strategy. The authors suggested that in order to enhance the compliance of mass chemotherapy, it was necessary to carry out mass chemotherapy in suitable seasons and to strengthen the health education activities.