尿毒净液治疗慢性肾功能衰竭临床研究

Clinical Research on Chronical Renal Failure with Treatment of Urea Nitrogen Cleaning Fluid.

目的:观察尿毒净液治疗慢性肾功能衰竭(CRF)的临床疗效。方法:将80例CRF住院患者随机分为治疗组50例和对照组(单用西药)30例,2组均给予控制血压、纠正酸中毒、水电解质紊乱、优质低蛋白、低磷饮食及对症处理,治疗组加用尿毒净液50mL,每日2次,或尿毒净液200mL保留灌肠,每日1次,以临床主要症状、血肌酐、尿素氮含量和内生肌酐清除率为观察指标,2个月为1个疗程,3个疗程后比较2组疗效。结果:治疗组的各项指标均明显优于对照组。结论:尿毒净液能有效延缓CRF进程,提高患者生存质量和生存期,值得临床推广应用。

Objective: To observe the clinical curative effect on Chronical Renal Failure (CRF) with self-made decoc-tion.Method:80 in-hospital cases were divided radomizationally into treatment group (TG) and control group (CG, basic treatnent group).TG were additionally give Urea Nitrogen Cleaning Fluid (UNCFO:50ml po bid or 200ml qd). Results:clin-ical indexes were main symptoms,Scr,BUN and endogenous crentinine clearance rate.The period of treatment were 2months ,The indexes were observed after 3 periods. All indexes in TG is much better than in CG.Condition:UNCF can retard the clinical process of CRF , promote quality of life and prolong life-respect.