1Leonard WJ. Role of JAK kinases and STATs in cytokine signal transduction[J]. Int J Hematal,2001,73(3) :271-277.
2Starr R,Willson TA, Viney EM, et al. A family of cytokine-inducible inhibitors of signalling[ J]. Nature, 1997,387(6636) :917-921.
3Endo TA, Masuhara M, Yokouchi M, et al. A new protein containing an SH2 domain that inhibits JAK kinases[ J]. Nature, 1997,387(6636) :921-924.
4Naka T,Narazaki M. Hirata M, et al. Structure and function of a new STAT-induced STAT inhibitor[ J]. Nature, 1997,387(6636) :924-929.
5Seki Y, Kubo M, Yoshimura A, et al. A mutant form of JAB/SOCSI augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through tile SOCS-box[J] .J Biol Chem,2001,276(44) :40746-40754.
6Yoshimura A,Ohkubo T. Kiguchi T, et al. A novel cytokine-inducible geme CIS encodes an SH2-containing protein that binds to tyrosinephosphorylated interleukin 3 and erythropoietin receptors[J]. EMBO J,1995. 14(12) :2816-2826.
7Nicholson SE,Willson TA, Farley A, et al. Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechamsms for inhibition of LIF and IL-6 signal transduction[ J]. EMBO J,1999,18(2) :375-385.
8Pezet A, Favre H, Kelly PA, et al. Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling[ J]. J Biol Chem, 1999,274(35) :24497-24502.
9Sakamoto H, Yasukawa H, Masuhara M, et al. A Janus kinase inhibitor, JAB, is an interferon-gamma-inducible gene and confers resistance to interferons[ J ]. Blood, 1998,92(5) : 1668-1676.
10Kaur N, Wohlhueter AL, Halvorsen SW. Activation and inactivation of signal transducers and activators of transcription by ciliary neurotrophic factor in neuroblastoma cells[J]. Cell Signal,2002,14(5) :419-429.
2Larsen L, Ropke C. Suppressors of cytokine signalling: SOCS [J]. APMIS,2002,110(12) : 833-44.
3Yoshimura A. Regulation of cytokine signaling by the SOCS and spred family proteins [ J ]. Keio J Med,2009,58(2) : 73 -83.
4Niemand C,Nimmesgern A,Haan S, et al. Activation of STAT3 by IL and IL-10 in primary human macrophages is differentially modulated by suppressorof cytokine signaling 3 [ J]. J Immunol,2003,170(6): 3263-3272.
5Baltayiannis G, Baltayiannis N, Tsianos EV. Suppressors of cytokine signaling as tumor repressors Silencing of SOCS3 facilitates tumor formation and growth in lung and liver [J]. J BUON, 2008,13(2) : 263 -265.
6Torisu T, Sato N, Yoshiga D, et al. The dual function of hepatic SOCS3 in insulin resistance in vivo [ J]. Genes Cells,2007,12(2) : 143 - 154.
