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乙型肝炎治疗药物研究进展 被引量:5

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摘要 本文综述了乙型肝炎治疗药物的新近研究进展。抗HBV治疗的研究表明,新的核苷类似物阿德福韦、恩替卡韦、Emtricitabine、Telbivudine等能有效抑制HBV;拉米夫定与免疫调节剂联合治疗可提高抗HBV的疗效;聚乙二醇化干扰素治疗乙型肝炎的效果优于标准干扰素;新的非核苷类药物Bay 41-4109及其类似物可抑制核衣壳的形成,从而抑制HBV的复制。
作者 吴亚松 吴昊
出处 《国外医学(流行病学.传染病学分册)》 2003年第6期332-334,共3页 Epidemiology Lemology Foreign Medical Sciences
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参考文献15

  • 1Marcellin P et al.N Engl J Med,2003;348(9):808 - 816.
  • 2Hadziyannis SJ et al. Nes Engl Med, 2003; 348 ( 9 ) : 800 - 807.
  • 3Goodman Z et al. Hepatology,2002;36:A373.
  • 4Schiff E et al. Hepatology, 2002; 36: A371.
  • 5Chang TTet al. Hepatology,2002;36:A300.
  • 6Gish R et al. Antimicrob Agents Chemother,2002;46(6) : 1734 - 1740.
  • 7Gish R et al. Hepatology,2002;36:A372.
  • 8Lai CL et al.AASLD,2001;ID:597.
  • 9Lai CL et al.AASLD,2002;36(4Pt 2):301A.
  • 10Lau GK et al. Hepatology,2002;36:A372.

同被引文献31

  • 1唐传久.阿德福韦双酯的合成与研究[J].安徽化工,2004,30(4):16-18. 被引量:4
  • 2任红.慢性乙型肝炎抗病毒治疗的若干问题[J].中华肝脏病杂志,2005,13(7):537-538. 被引量:32
  • 3Deres K, Scbroder CH, Paessens A, et al. Interfering with capsid formation:a practicable antiviral strategy against hepatitis B virus[J] ? Hepatology, 2004, 39(3): 838-840.
  • 4Deres K, Scbroder CH, Paessens A, et al. Inhibition of hepatitis B virus replication by drug induced depletion of nucleocapsides[J]. Science, 2003, 299(5608): 893-896.
  • 5Stray SJ, Zlomick A. BAY 41-4109 has multiple effects on hepatitis B virus capsid assembly[J]. J Mol Recognit, 2006, 19(6):542-548.
  • 6Wu GY, Zheng XJ, Yin CC, et al. Inhibition of hepatitis B virus replication by Bay 41-4109 and its association with nucleocapsid disas sembly[J]. J Chemother, 2008, 20(4): 458-467.
  • 7Weber O, Schlemmer KH, Hartmann E, et al. Inhibition of human hepatitis B virus (HBV) by a novel non-nucleosidic compound in a transgenic mouse model[J]. Antiviral Res, 2002, 54(2): 69-78.
  • 8Morrey JD, Bailey KW, Korba BE, et al. Utilization of transgenic mice replieating high levels of hepatitis B virus for antiviral evaluation of lamivudine[J]. Antiviral Res, 1999, 42(2): 97-108.
  • 9SEIFER M,PATTY A,FARAJ A,et al.In vitro studies on the mechanism of action of L-nucleoside inhibitors of hepatitis B virus replication reveal differences between LdT and lamivudine[J].Hepatology,2001,34(S1):635A.
  • 10KIM JW,PARK SH,LOUIE SG.Telbivudine:a novel nucleoside analog for chronic hepatitis B[J].Ann Pharmacother,2006,40 (3):472-478.

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