左氧氟沙星治疗老年人常见感染的评价

Levofloxacin in Treatment of Infections of Elder People

目的 评价左氧氟沙星治疗老年人肺部感染、肠道感染及尿路感染的疗效 ,抗菌谱及不良反应。方法 左氧氟沙星治疗老年人肺部感染 2 0例、尿路感染 6例、肠道感染 4例 ,给予左氧氟沙星 30 0～ 6 0 0mg/d ,观察临床症状及实验室变化、细菌学检查 ,评价临床疗效及细菌学疗效。结果 临床总有效率 86 6 % ,细菌清除率为88 9% ,不良反应较少 ,且能耐受。结论 左氧氟沙星治疗老年人肺部感染、肠道感染及尿路感染疗效佳 ,使用安全。

OBJECTIVE To evaluate the efficacy and safety of levofloxacin (Cravit) in treatment of bacterial infections of elder people. METHODS The total number of clinical evaluated subjects was 30 elder patients, including 20 with pulmonary infection, 6 with urinary tract infection and 4 with intestinal infection. The dose of levofloxacin was 300-600mg, bid. After that to observe clinical symptoms and laboratory changes, to do bacterial inspections and to evaluate clinical efficacy in treatment of bacterial infections. RESULTS Clinical efficacy rate was 86.6%, microbiologic eradication rate was 88.9%. The incidence of adverse reaction was quite low. CONCLUSIONS It is concluded that levofloxacin has an excellent clinical efficacy and good safety profile in treating elder patients with bacterial infections.