摘要
目的分析总结老年慢性阻塞性肺部疾病(以下简称COPD)合并2型糖尿病(以下简称T2DM)的临床特点及治疗原则。方法回顾性总结分析了15年中451例60岁以上COPD合并T2DM患者的临床症状、体征、实验室资料。结果本组男性多于女性,在COPD基础上并发T2DM多见276/175(占总数的61.2%),此症临床表现不典型,以病情重,疗效差、病程长、易反复为其特点。二病并存病情复杂而又严重的原因常为多因素,其间有些因素互相叠加,但主要是高血糖状态、低氧血症及免疫功能失调三方面。结论1.COPD合并T2DM的发病率有逐年增高趋势,本组近5年发病数占15年的总数的一半以上(57.2%)应引起同道们重视。2.正确弄清和认识这些因素间的关系,有利于预防和治疗这组疾病。病因治疗是否及时,是否同时进行,关系到本病的临床疗效和预后,而T2DM控制更是COPD稳定的条件。
Objective To analyze the clinical characteristics and the therapeutic principles of aged COPD with T2DM. Methods Retrospective analyses were performed about the clinical history, signs and laboratory results of 451 cases of COPD over 60 years of age or older with T2DM during the recent 15 years. Results There were more men than women in our series(276/175).It was more common that the patients' T2DM were developed on the basis of COPD. These cases had several special characteristics, such as atypical clinical findings, serious condition, poor curative effect, long clinical course and easy recurrence. The reasons of complicated and serious condition in COPD with T2DM were multiple. Some factors had overlapping effect on one another, eg hyperglycemia, hypoxemia and immunodysfunction were the chief factors. Conclusions 1. The incidence of COPD 60 years of age or older with T2DM is going up year by year. We should take it seriously because cases coming to us in recent five years are more than half of those in the past fifteen years(57.2%). 2. It is beneficial to us to prevent and treat this disease after having a correct understanding of those factors. Meanwhile, whether these factors are treated timely and simultaneously or not, there is a close relationship with the prognosis of this disease. Furthermore, T2DM under proper control makes the condition of COPD more stable too.
出处
《老年医学与保健》
CAS
2003年第4期236-237,242,共3页
Geriatrics & Health Care
关键词
肺疾病
阻塞性
糖尿病
非胰岛素依赖型
并发症
Lung diseases, obstructive
Diabetes mellitus,non-insulin-dependent
Complications