几种免疫球蛋白与哮喘、慢性支气管炎的关系

The Relation between Asthma,Chronic Bronchitis and Several Kinds of Immunoglobulins

用三抗体免疫放射分析法测定57例哮喘患者发作期血清IgE,同时用放射免疫双抗法测定血清IgG、IgA、SIgA 及唾液SIgA 水平,并与同期122例慢支作对照分析。结果:哮喘发作期IgE 水平显著升高,IgA 水平明显降低,P 值均<0.01。对哮喘有诊断意义。

While using triantibody Immunoradiometric assay to determine the serium IgE during the at-tacking period in 57 cases of asthma biantibody radioimmunoassay was adopted to determine the lev-el of serium IgG,IgA,SIgA and saliva SIgA,and control analysis was made in 122 cases of chronicbronchitis in the corresponding period.The result demonstrates that when the asthma attack occurs,the level of IgE rises markedly and IgA declines obviously.The P values are all less than 0.01.Thatis significant to asthma diagnosis.