血压与冠心病患病关系的探讨

The Relationship between Pulse Pressure and Coronary Heart Disease

目的 :探讨收缩压 (SBP)、舒张压 (DBP)和脉压 (PP)在冠心病 (CHD)患病危险上的差别。方法 :调查2462例40～91岁驻京部队干部的血压水平和CHD患病危险进行单因素和多因素logistic回归分析。结果 :中老年人CHD患病危险和SBP和PP呈正相关 ,与DBP无关 ;单因素分析将SBP水平分为5个亚组 ,SBP130～、140～和≥160mmHg 的CHD患病危险分别是SBP<120mmHg 的2 433、4 345和5 313倍 ;将PP水平分为4个亚组 ,PP为50～和≥60mmHg 组的CHD患病危险分别是PP<40mmHg的4 026和7 106倍。多因素分析显示血压成分中PP与CHD患病危险的比值比 (OR)为1 014。结论 :SBP和PP是预测中老年人CHD患病危险的一个较好指标 ,而PP是中老年人CHD发生的独立危险因子。

Objective:To analyze the relationship between blood pressure levels and coronary heart diseases(CHD)in middle and old aged people,and to evaluate the predicting value of systolic blood pressure(SBP),diastolic blood pressure(DBP)and pulse pressure(PP)in CHD.Methods:Data of blood pressure in 2 462 middle and old aged army people were studied.The blood pressure levels and other risk factors of CHD were analyzed by logistic mono and multifactor regression model.Results:There was a positive correlation between the incidence of CHD and SBP and PP.SBP levels were divided into 5 groups,and the odds ratio(OR)of CHD in 130～,140～and over 160 mmHg groups were 2.433,4.345 and 5.313 times compared with that in <120 mmHg group respectively.The OR of PP levels in 50～and over 60 mmHg groups were 4.026 and 7.106 times compared with that in <40 mmHg group respectively.The ratio of PP to CHD was 1.014 by the analysis of multifactor regression model.Conclusion:SBP and PP are better predictors for predicting CHD.PP is the independent risk factor in middle and old aged CHD.