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牛自体皮肤移植试验研究 被引量:2

Experimental Study on Autogenous Skin Transplantation of Cattle
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摘要 为探讨自体皮片的嵌植效果 ,在实验牛臀部人为制造 1 1 .2 cm× 1 5cm、1 1 cm× 1 5cm两个全层皮肤缺损创 ,造创后用涂有蒽诺沙星药膏的无菌纱布覆盖创面 ,每隔 1天换 1次药。5~ 6d后创面出现肉芽组织 ,1 2 d时肉芽组织覆盖整个创面 ,并与周围皮肤缘相平 ,肉芽平整 ,有光泽。造创后 1 3 d开始植皮。用自制的取皮工具自颈部取皮 ,取皮面积约等于受皮区面积的1 / 1 0。将取下的皮肤修剪成大约有 5mm2的小皮块用于植皮 ,采用嵌植法将皮块移植于创面。左右创面分别为 90、78块。结果 :植皮 2 4d后 ,原来皮肤凹陷已经长平 ,新生表皮覆盖整个创面 ,色素区扩大盖满了整个创面 ,创面呈黄色 ,在色素较多的地方有毛生长。结论 :自体小皮块嵌植法简单易行 ,皮块成活率高 ,可大大缩短皮肤大面积缺损创的愈合时间。 Objective To discuss the effects of the intermingled transplantation with autogenous skin.Methods Author made two wounds of absent skin on the experimental cattle's buttocks,the areas of the two wound were 11.2 cm×15 cm,11 cm×15 cm,and covered with sterile gauze daubed by enrofloxacinum,changed bandage every 2 days.At the 5th-6th day,the granulation tissues appeared on the wounds,at the 12th,the granulation tissues overed all the wounds and paralleled with the brink of the surrounding skin,the granulation tissues were smooth and glossy.Author transplanted skin at the 13th day,and taken skin from neck of cattle with the tool made by ourselves. The taking skin area was 10% of the tansplanting skin area.The taking skin was pruned to the 5 mm^2 skin grafts,putting the skin grafts into the wounds by inlying transplantation.The skin grafts number of the left and right wounds respectively was 90 and 78.Results After 24 days,the new epidermis had covered the complete wounds and the area of pigment expanded to all the wounds,the wounds were yellow and the deposited pigment regin had hair growing.Cnclusion The inlying transplantation with autogenous skin grafts proved to be easy feasible,the survival rate is high and enormously shortened the healing time of the damaged skin wounds.
作者 杨光 李振清
出处 《动物医学进展》 CSCD 2003年第6期106-108,共3页 Progress In Veterinary Medicine
关键词 自体 皮肤移植 试验 蒽诺沙星药膏 无菌纱布 cattle skin graft inying transplantation
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