不同产地冬虫夏草清除羟自由基作用的研究

Scavenging effect of Cordyceps growing in different environment on hydroxyl radical

目的 比较不同产地冬虫夏草对羟自由基的清除作用。方法 采用邻二氮菲 - Fe2 +氧化法检测不同产地冬虫夏草水提液对 H2 O2 / Fe2 + 体系产生的羟自由基的清除作用。结果 来自西藏那曲地区、云南滇西北地区和四川川西北地区的冬虫夏草均对 Fenton反应产生的羟自由基有显著或极显著的清除作用 ,且来自不同微生态环境的样品之间的清除作用差异比来自不同主产区样品之间的清除作用差异更明显。结论 冬虫夏草水提液有明显地清除羟自由基的作用 ,且微生态环境对该作用有较大的影响。

Object To investigate and compare the scavenging effect of Cordyceps growing in different environment on hydroxyl radical. Methods 10-Phennanthroline-Fe 2+ oxidative assay was used to observe the effect of scavenging hydroxyl radical from H_2O_2/Fe 2+ system by the aquenous extracts of Cordyceps. Results Cordyceps from Naqu of Xizang,northwest Yunnan,and northwest Sichuan all showed us the significant effect on scavenging of hydroxyl radical produced from Fenton Reaction. The biggest values of MDR among Cordyceps specimens from various microecological environment surpassed that among specimens of Naqu of Xizang,northwest Yunnan,and northwest of Sichuan. Conclusion The aquenous extracts of Cordyceps could scavenge the hydroxyl radical from Fenton Reaction. The microecological environment for Cordyceps growing has an significant effect on its scavenging action.