山西地区102例重症严重急性呼吸道综合征患者临床分析

Clinical analysis of 102 critical SARS cases in Shanxi

目的 分析山西地区 10 2例重症严重急性呼吸道综合征 (SARS)患者的临床特征、治疗效果和预后。方法 对山西地区 2 0 0 3年 3月 7日至 6月 4日 10 2例重症 SARS患者的临床资料进行总结 ,并进行统计学分析。结果 10 2例患者男性 4 8例 (4 7% ) ,女性 5 4例 (5 3% ) ;主要临床表现为发热 (10 0 % )、咳嗽 (5 5 % )、呼吸困难 (4 4 % )。早期白细胞数平均 (6± 4 )× 10 9/ L ,淋巴细胞平均 (16± 12 ) % ,10 2例都有胸部 X线检查异常。疾病的早期使用呼吸机 ,心理治疗可阻止病情进展 ,多因素分析显示 :不良预后影响因素是高龄、无心理治疗。结论 重症 SARS男女发病大致相等 ,无特征性临床表现 ,早期使用呼吸机 ,心理治疗有效 ,年龄。

Objective To investigate the clinical characteristic prognosis of 102 cases of critical SARS in Shanxi.Methods The clinical data of 102 critical SARS cases were analyzed,and at last statistical analysis of the cases was done.Results In this group 48 were male and 54 female.The main clinical manifestations included fever (100%),cough (55%),dyspnea (44%).WBC′s average was (6±4)×10 9/L,and the mean lymphocyte (16±12)%.All the cases had abnormal chest radiographs.At the early stage application of non-invasive mechanical ventilation and heart therapy helped stop the progress of disease.A multifactorial analysis showed adverse outcome resulted from advanced age and having no psychotherapy.Conclusion Critical SARS has not its own characteristic clinical manifestations.Effective treatment includes oxygen support and psychological therapy,age and psychotherapy are the predictor of the outcome.