1Leek RD.Bcl-2 in normal human breast and carcinoma,association with oestrogen receptor-positive,epidermal growth factor receptor-negative tumours and in situ cancer.Br J Cancer,1994,69∶135.
2Sierra A,Castellsague X,Escobedo A,et al.Bcl-2 with loss of apoptosis allows accumulation of genetic alterations:a pathway to metastatic progression in human breast cancer.Int J Cancer,2000,89∶142-147.
3Ralph S,David ML.In search of the tumour-suppressor functions of BRCA1 and BRCA2.Nature,2000,408∶429-432.
4Miki Y,Swensen J, Shattuck Eidens D,et al.A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.Science,1994,26∶66.
5David C,Yi W,Jun Q,et al.Requirement of ATM-dependent phosphorylation of BRCA1 in the DNA damage response to double-strand breaks.Science,1999, 286∶1162-1166.
6Deng CX ,Brodie SG.Roles of BRCA1 and its interacting proteins.Bioessays,2000,22∶728-737.
7Welcsh PL,Owens KN,King MC.Insight into the function of BRCA1 and BRCA2.Trends Genet,2000,16∶69-74.
8Chen JJ,Sliver D,Cantor S,et al.BRCA1,BRCA2,and Rad51 operate in a common DNA damage pathway.Cancer Res,1999,59(7 Suppl)∶1752-1756.
9Scully R.Genetic analysis of BRCA1 function in a defined tumour cell line.Mol Cell,1999,4∶1093-1099.
10Cordeiro-Stone M,Makhov AM,Zaritskaya LS,et al.Analysis of DNA replication forks encountering a pyrimidine in the template to the leading strand.J Mol Biol,1999,289∶1207-1218.
2Sternlicht MD, Bissell MJ, Werb Z. The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter [ J ]. Oncogene, 2000,19(8) :1102-1113.
3Lebeau A, Nerlich AG, Sauer U, et al. Tissue distribution of major matrix metalloproteinases and their transcripts in human breast carcinomas [ J ]. Anticancer Res, 1999,19 ( 5 B) :4257-4264.
4Remacle AG, Noel A, Duggan C, et al. Assay of matrix metalloproteinases types 1, 2, 3 and 9 in breast cancer [J]. Br J Cancer, 1998,77(6) :926-931.
5Visvader JE,Lindeman GJ.Cancer stem cells in solid tumours:accumulating evidence and unresolved questions[J].Nat Rev Cancer,2008;8(10):755-768.
6Al-Hajj M,wicha MS,Benito-Hernandez A,et al.Prospective identification of tumorigenic breast cancer cells[J].Proc Natl Acad Sci USA,2003;100(11):3983-3988.
7Ponti D,Costa A,Zaffaroni N,et al.Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties[J].Cancer Res,2005;65(13):5506-5511.
8Sheridan C,Kishimoto H,Fuchs RK,et al.CD44+/CD24-breast cancer cells exhibit enhanced invasive properties:an early step necessary for metastasis[J].Breast Cancer Res,2006;8(5):R59.
9Nakshatri H,Srour EF,Badve S.Breast cancer stem cells and intrinsic subtypes:controversies rage on[J].Curr Stem Cell Res Ther,2009;4(1):50-60.
10Ginestier C,Hur MH,Charafe-Jauffret E,et al.ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome[J].Cell Stem Cell,2007;1(5):555-567.
