糖尿病患者慢性并发症患病率及相关因素分析

The morbidity of chronic diabetic complication with logistic regression analysis of related potential risk factors

目的 探讨糖尿病患者慢性并发症的患病情况以及相关因素。方法 对浙江省1083例糖尿病患者慢性并发症的回顾性调查资料进行描述性分析,并采用logistic回归对其相关因素进行深入分析,初步建立慢性并发症相关因素的数学模型。结果 糖尿病患者慢性并发症有心血管疾病、眼科疾病、肾病、感觉神经疾病、植物神经疾病、脑血管疾病、下肢血管疾病和运动神经疾病。主要的相关因素有糖尿病病程、高血压病程、年龄、诊断年龄、血压、空腹血糖、餐后2 h血糖、糖化血红蛋白、甘油三酯、血清总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇等。结论 文中采用的分析方法适用于其他慢性病并发症的患病情况和相关因素的研究;在此基础上可以建立其鉴别函数,为临床上的诊断提供参考依据。

Objective To investigate the morbidity and potential risk factors of chronic diabetic complication in Zhejiang province. Methods In the paper the morbidity of diabetic chronic complication was illustrated, using descriptive statistics. The potential risk factors of diabetic chronic complication were studied with logistic regression modeling, using data from a large retrospective study involving 1083 patients from two hospitals in Zhejiang province. Results Principal chronic diabetic complications were found to be cardiovascular diseases, ophthalmic diseases, nephropathy, esthetic diseases, plant nerve diseases, cerebral blood vessel diseases, limbsblood vessel diseases and athletic nerve diseases. The principal potential risk factors would include the courses of diabetes and hypertension, age, age being diagnosed, blood pressure, baseline blood glucose, two hour blood glucose after dietary, HBAIC, nitroglycerine, cholesterol, high density lipoprotein cholesterol and low density lipoprotein cholesterol. Conclusion The analytic method used in the paper was fit for the study of morbidity and potential risk factors of other chronic diseases complication and the discriminant function could be built for clinical diagnosis.