期刊文献+

小剂量美托洛尔治疗慢性收缩性心力衰竭的疗效观察 被引量:9

Curative effect observation of small dose of Metoprol treat of chronic contractibility heart failure
下载PDF
导出
摘要 目的 观察美托洛尔对慢性收缩性心力衰竭患者的心功能及左心室射血分数的影响。方法 选择缺血性和非缺血性慢性收缩性心力衰竭患者 98例 ,左室射血分数≤ 0 .4 5 ,心功能 (NYHA)Ⅱ~Ⅳ级 ,常规治疗 ,病情基本稳定的基础上随机分为治疗组和对照组。治疗组给美托洛尔 2 5~ 5 0mg/d。两组治疗 6个月 ,观察用药前、后 1个月、3个月、6个月临床症状及心功能指标的变化。结果 美托洛尔使患者症状和心功能改善 ,左室舒张末期内径缩小 ,左室射血分数上升 ,较对照组改善更明显 (P <0 .0 5 )。结论 美托洛尔治疗慢性收缩性心力衰竭能显著改善患者心功能 ,增加左室射血分数 ,改善预后。
出处 《中国现代医学杂志》 CAS CSCD 2003年第23期100-101,共2页 China Journal of Modern Medicine
  • 相关文献

参考文献4

二级参考文献21

  • 1Eichhorn EJ,Bristow MR.Medical therapy can improve the biological properties the chronically failing heart: a new era in the treatment of heart failure[].Circulation.1996
  • 2Whorlow SL,Krum H.Meta-analysis of effect of β-blocker therapy on mortality in patients with New York Heart Association class Ⅳ chronic congestive heart failure[].The American Journal of Cardiology.2000
  • 3Metra M,Giubbini R,Nodari S,et al.Differential effects of betablocker in patients with heart failure: a prospective, randomized,double-blind comparison of the long-term effects of metoprolol versus carvedilol[].Circulation.2000
  • 4Bisognano JD,Weinberger HD,Bohlmeyer TJ,et al.Myocardialdirected overexpression of the human beta-1 adrenergic receptor in transgenic mice[].Journal of Molecular and Cellular Cardiology.2000
  • 5Bristow MR.Mechanism of action of beta-blocking agents in heart failure[].The American Journal of Cardiology.1997
  • 6Braunwald E,Bristow MR.Congestive heart failure[].Circulation.2000
  • 7The Beta-blocker Evaluation of Survival Trial Investigators.A trial of the beta-blocker bucindolol in patients with advanced chronic heart failure[].The New England Journal of Medicine.2001
  • 8Yancy CW,Fowler MB,Collucci WS,et al.Race and the response to adrenergic blockade with carvedilol in patients with chronic heart failure[].The New England Journal of Medicine.2001
  • 9MERIT-HF Study Group.Effect of metoprolol CR/XL in chronic heart failure: metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT HF)[].The Lancet.1999
  • 10Parcker M,Coats AJS,Fowler MB,et al.Effect of carvedilol on survival in severe chronic heart failure[].The New England Journal of Medicine.2001

共引文献582

同被引文献49

引证文献9

二级引证文献20

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部