摘要
综述三唑类抗真菌药物的构效关系 ,介绍新结构类型的三唑类抗真菌药物。为进一步探讨该类药物的结构优化 ,开发更多更新的广谱、高效、低毒的抗真菌药物 ,提供研究思路。
The structure activity relationship of triazole antifungals was reviewed, and antifungal triazoles based on new structures were introduced so as to contribute to further structural optimization and development of them.
出处
《药学进展》
CAS
2003年第6期336-340,共5页
Progress in Pharmaceutical Sciences
基金
国家"86 3"项目 (NO .2 0 0 2AA2 330 91)
军队"十五"指令性课题 (NO .0 110 5 7)
关键词
三唑类
抗真菌药物
构效关系
结构优化
抗菌活性
Triazole antifungal
Structure activity relationship
Structural optimization
Antifungal activity