急性脑梗死患者血清钙、镁含量及其临床意义

Serum Calcium and Magnesium Level in Acute Cerebral Infarction and Its Clinical Significance

目的 探讨血清钙、镁含量与急性脑梗死的关系及其临床意义。方法 检测 75例确诊为急性脑梗死患者早期和 2周时血清钙、镁含量 ,并选取 6 3例非急性脑梗死患者作对照研究 ,对脑梗死患者按临床神经功能缺损程度评分 ,将其划分为轻型脑梗死、中型脑梗死和重型脑梗死三组。结果 与对照组比较 ,患者各组血清钙、镁含量均降低 (P<0 0 1) ,轻型脑梗死、中型脑梗死和重型脑梗死组之间血清钙、镁含量亦有明显差异 ,治疗 2周后患者组血清钙、镁含量比原先有较大回升 (P <0 0 1) ,但与对照组比较仍降低 (P <0 0 1)。结论 急性脑梗死患者血清钙、镁含量降低 ,其降低程度与临床神经功能缺损程度评分相关 ,随着病情好转 ,血清钙。

Objective To explore the relationship bet ween serum calcium and magnesium concentration and acute cerebral infarction and elucidate its clinical significance.Methods The serum calcium and m agnesium concentrtion was determined in 63 healthy people(control group) and 75 acute cerebral infarction patients before and after two weeks of study.According to the clinical nerve deficiency scale,the cerebral infarction patients were di vided into tree subgroups:mild cerebral infarction,moderate cerebral infarction and severe cerebral infarction.Results Compared with co ntrol group,serum calcium and magnesium concentrations in all three groups of ac u te cerebral infarction patients were significantly lower ( P <0 01).And s erum calcium and magnesium concentrations were negatively correlated with severi t y of the disease.Serum calcium and magnesium concentrations increased after two w eek's treatment ( P <0 01),though they were still lower than those in co ntrol group ( P <0 01).Conclusions Serum calcium and magnesium concentrations decreased in acute cerebral infarction patients,th e degree of decrease was correlated with the clinical nerve deficiency scale.The concentration increased with patients recovery.