26例女性假两性畸形分析

ANALYSIS OF 26 CASES OF FEMALE PSEUDOHERMAPHRODITISM

女性假两性畸形26例,染色体均为46,xx。未成年者其社会性别女性11例,男性7例;成年者女性6例,男性2例。因生后阴蒂大而将其中9例作为男孩抚养。经查明,1例为母孕期服大量雄激素所致。5例开腹探查发现内生殖器均为子宫及卵巢,而地塞米松抑制试验亦为阳性,6例查尿17—酮均高于正常值。这种病人尽管外生殖器有不同程度男性化,而性腺及内生殖器均为女性。此类患者一旦确诊,不需要再行腹探查,早治疗可使患儿得到正常的生长发育。

The chromosomes of 26 cases of female pseudohermaphroditism were of 46xx. In the impuberism patients, 11 was female and 7 was male in social sex; in the adult patients, 6 was female and 2 was male. Because of clitoridauxe at their birth 9 was brought up to boys. One was caused by large dose of androgenic hormones during pregnency. The internal genitals of 5 cases proved to be wombs and ovaries by laparotomy and the dexame thasone suppressien test on them was positive. The results of urine 17—kelosteroid of 6 patients were beyond normal value. Although external genitals were virilescent to certain degree, their sexual gland and internal genitals were female. Once a definite diagnosis is made, the patients should be treaded as early as possible so that the sick children can have normal menstruation and be pregnant.