血清白蛋白水平与高血糖的相关性研究

Research on the Relationship Between Human Serum Albumin Level and the Incidence of Hyperglycemia

目的 探讨血清白蛋白水平与高血糖的相关性。方法 对 2 0 0 0例不同疾病患者临床生化指标进行回顾性研究。结果 与血清白蛋白水平正常 (3 3～ 55g/L)者比血清白蛋白水平低下 (<3 3g/L)者高血糖出现率明显增加 (P <0 .0 5) ;血清白蛋白水平分成 10个等级后 ,呈现出白蛋白水平等级越低高血糖出现率越高的趋势 ,且白蛋白等级为 1～ 3级者 (<3 8.5g/L)高血糖出现率较高 (P <0 .0 5) ,经Spearman等级相关分析呈负相关 (P <0 .1)。

Objective To analysis relationship between human seru m albumin level and the incidence of hyperglycemia. Methods A r etrospective cohort study of 2000 patients with or not with diabetes mellitus wa s performed, all data were from laboratory records. Results The i ncidence of high glucose level was high in patients with low serum albumin level (<33 g/L) than that in patients with normal level (33～55 g/L)(P<0.05). A rank negative correlation between the grade of serum albumin level (divided int o ten grades) and the incidence of high glucose was found in 2000 patients (r s =0.6364,P<0.1). Conclusions Our findings imply that serum albumin level should be taken into consideration when evaluating serum albumin a s a risk factor for diabetes mellitus.