剪切波瞬间弹性成像技术评估慢性乙型肝炎患者肝纤维化与肝功指标相关性研究

Correlation of liver elasticity evaluated by shear wave elastrography and liver function index in patients with chronic hepatitis B

目的:探讨剪切波瞬间弹性成像技术检测慢性乙型肝炎患者肝弹性值及与肝功能指标之间的相关性。方法:2015-05~2015-11在我院就诊的慢性乙型肝炎患者200例,采用深圳市一体医疗股份公司生产的ET-CD-I超声肝硬化检测仪进行肝纤维化程度检测,获得肝纤维化弹性值,并观察受检者肝功相关指标。选择同期在体检中心体检的100例志愿者作为对照组。结果:慢性乙型肝炎组肝纤维化弹性值均高于正常对照组(P<0.05),且与肝功能相关指标比较有相关性。结论:剪切波瞬间弹性成像技术可定性、定量反应乙肝患者肝纤维化程度,是一种无创、快捷、客观、定量评估肝纤维化的方法。

Objective:To explore the correlation of liver elasticity evaluated by shear wave elastrography(SWE)and liver function index in patients with chronic hepatitis B.Methods:A total of 200 patients with chronic hepatitis B admitted in our hospital from May to November of 2015 were included in our study.Liver elasticity was detected by SWE while liver function was evaluated.All together 100 healthy volunteers were selected as control.Results:Liver elasticity was higher in chronic hepatitis B group than that in control group(P <0.05),and correlated to liver function index.Conclusion:SWE is a minimal invasive,rapid,objective technique in the evaluation of liver fibrosis which can qualitatively and quantitatively indicate liver fibrosis in patients with chronic hepatitis B.