摘要
目的:随着社会经济的迅猛发展,人民生活水平的提高及生活方式的改变,近年来乳腺肿瘤已成为女性常见疾病,尤其是乳腺癌已成为女性最常见的恶性肿瘤之一,严重影响女性的身心健康甚至危及生命。乳腺癌的发生发展、转移扩散是多基因参与,多阶段多步骤完成的复杂过程。近年来,国内外学者对MLK3在恶性肿瘤方面的研究日益加深,已有文章报道了MLK3与恶性肿瘤发生与发展机制的信号传导有关。本文通过国内外相关文献进行归纳总结,对MLK3与乳腺癌的关系及其研究进展作一综述。
With the rapid development of social economy,improvement of people's living standard and change of life style,in recent years,breast tumors have become the most common disease of women,especially breast cancer has become one of the most common malignant tumor in women,has serious impact on women's health and even life-threatening.The development and metastatic spread of breast cancer is a complex process involving multiple genes,multiple stage and multiple steps.In recent years,domestic and foreign scholars study of MLK3 in malignant tumor is growing,articles have been reported that the relevance between MLK3 and signal transduction of malignant tumor occurrence and development mechanism.Related literature at home and abroad are summarized in this paper,reviewe the progress in research on MLK3 and its relationship with breast cancer.
