放疗联合唑来膦酸治疗恶性肿瘤骨转移疼痛的疗效分析

Analysis the curative effect of radiotherapy combined with zoledronic acid in the treatment of malignant tumor bone metastases pain

目的:分析放疗联合唑来膦酸治疗恶性肿瘤骨转移疼痛的疗效。方法:收治恶性肿瘤骨转移疼痛患者61例,随机分为两组,治疗组33例,给予放疗联合唑来膦酸治疗;对照组28例,只给予放疗治疗。结果:33例恶性肿瘤骨转移患者在完成治疗后,骨痛症状均有减轻趋势。结论:放疗与唑来膦酸有效结合,通过不同途径抑制破骨细胞的活性,从而控制骨转移瘤的进展,有效提高患者生活质量,延长生命期。

Objective:To analysis the curative effect of radiotherapy combined with zoledronic acid in the treatment of malignant tumor bone metastases pain.Methods:To admit 61 cases of patients with malignant tumor bone metastases pain,there were randomly divided into two groups,33 cases in the treatment group were gived radiotherapy combined with zoledronic acid therapy, 28 cases in the control group were only given radiotherapy treatment.Results:33 cases of patients with malignant tumor bone metastases pain after the completion of treatment,the symptom of pain were relieved trend.Conclusion:Radiotherapy effectively combined with zoledronic acid,inhibit osteoclast activity through different pathways,thus to control the progress of bone metastasis, improve the quality of patients' life,prolong the life period,is worth to further promote.