摘要
目的:探讨自体细胞因子诱导的杀伤细胞治疗急性白血病的临床疗效,为医院提高急性白血病的整体诊治水平提供重要的数据参考。方法:收治急性白血病患者68例,作为研究对象,并按照入院先后顺序,将其分为对照组和观察组,每组34例,其中对照组单用化疗治疗,观察组在此基础上加用自体细胞因子诱导杀伤细胞治疗,分析和比较两组的临床治疗情况。结果:经研究发现,观察组34例患者中,共有32例获得完全缓解,治愈率94.12%;2例发生骨髓抑制期感染(5.88%);并且无1例死亡;分别与对照组的27例(82.35%)、7例(20.59%)和4例(11.76%)比较,差异均有统计学意义(P<0.05)。结论:给予急性白血病患者自体细胞因子诱导的杀伤细胞治疗,能够有效提高临床治疗效果,控制骨髓抑制期感染率,提高患者的生存质量,具有较高的临床应用价值。
Objective:To discuss the clinical efficacy of the somatic factor induced killer cells in treating acute leukemia,to provide an important reference data for thehospital improve the overall level of diagnosis and treatment of acute leukemia.Methods:To admit 68 cases of acute leukemia patients from October 2011 to October 2013,as the object of study,and in accordance with the order of admission,divided into the observation group and the control group,34 cases in each group,the control group was treated with chemotherapy alone,the observation group on this basis used the somatic factor induced killer cells therapy,analyze and compare the clinical treatment condition of the two groups.Results:The study found that,the observation group of 34 cases,there were 32 cases achieved complete remission,the cure rate was 94.12%;2 cases had bone marrow inhibition phase of infection(5.88%);and no death in 1 cases;compared with 27 cases(82.35%),7 cases(20.59%) and 4 cases(11.76%),in the control group,the differences were statistically significant(P<0.05).Conclusion:The somatic factor induced killer cells in treating acute leukemia,can effectively improve the clinical treatment effect,control of bone marrow suppression period infection rate,improve the quality of life of patients,with a high clinical value,is worth of further promotion.
