利凡诺联合米非司酮应用于初产妇中孕引产的临床疗效观察

Observation of the clinical curative effect of rivanol combined with mifepristone for induced abortion in mid-term pregnancy of primipara

目的:研究分析在初产妇中孕引产中使用利凡诺联合米非司酮的临床措施和相应效果,为此类患者临床治疗提供理论依据。方法:收治引产产妇134例,根据产妇孕中引产采用的不同药物,将其分为两组,对照组60例,孕中单纯使用利凡诺引产,观察组74例,孕中引产在采用利凡诺的基础上加用米非司酮,比较两组产妇注射药物至宫缩开始的时间、分娩时间、产后出血情况、产程时间、疼痛程度和软产道撕裂等指标情况。结果:观察组产妇的引产时间、总产程明显短于对照组,组间比较差异具有统计学意义(P<0.05),且观察组产妇产后的疼痛程度、软产道撕裂情况明显少于对照组(P<0.05)。结论:初产妇中孕引产中采用利凡诺联合米非司酮具有明显的扩张和软化宫颈的作用,能够有效缩短引产时间和总产程,降低产后宫颈裂伤和疼痛的发生率,疗效显著。

Objective:To explore the clinical curative effect of rivanol combined with mifepristone for induced abortion in mid-term pregnancy of primipara,in order to provide theoretical basis for its clinical treatment.Methods:We selected 134 cases of maternal with induced labour in 2010 March to 2012 November.These patients were divided into two groups according to different medicine in induced labour.In 60 cases of the control group,rivanol was simply used in induced labour.In 74 cases of the observation group,rivanol combined with mifepristone were used in induced labour.The indicators of two groups of patients were compared,such as injection of drugs to the contraction starting time,delivery time,postpartum hemorrhage,labor time,the degree of pain and soft birth canal laceration and so on.Results:The induction time and total duration of the observation group were shorter than the control group,the difference was statistically significant(P<0.05).The degree of pain and soft birth canal laceration of the observation group were significantly less than that of the control group(P<0.05).Conclusion:In induced abortion in mid-term pregnancy of primipara,the use of rivanol combined with mifepristone had obviously dilatation and softening effect of the cervix, can effectively shorten the labor time and labor,reduce the incidence of postpartum cervical laceration and pain.Its curative effect was remarkable.