摘要
目的:分析婴儿痉挛症的临床诊断及治疗。方法:收治IS患儿35例,所有患儿均接受治疗,用丙戊酸钠10例,静脉用促肾上腺皮质激素8例,托吡酯5例,甲泼尼龙2例,拉莫三嗪5例,丙种球蛋白5例。结果:14例(40%)完全缓解,10例(28.5%)偶发抽搐,5例(14.3%)仍有痉挛发作,5例(14.3%)有发展成为Lennox-Gastaut综合征的倾向,1例(2.8%)随访失败。结论:对IS的深入研究和探索,有利于临床合理治疗,改善预后。
Objective:To analyze clinical diagnosis and treatment of infantile spasms.Methods:35 children with IS were treated in our hospital,10 cases were given sodium valproate,8 cases were given adrenocorticotropic hormone intravenous injection,5 cases were given topiramate,2 cases were given methylprednisolone,5 cases were given lamotrigine,5 cases were given gamma globulin.Results:14 cases were complete remission(40%),10 cases were occasional tics(28.5%),5 casesstill had seizures(14.3%),5 cases have the trend to become Lennox-Gastaut syndrome(14.3%),1 case lost to follow-up(2.8%).Conclusion:The research and exploration of IS in depth is benefit to reasonable clinical treatment and improve the prognosis.
关键词
婴儿痉挛症
临床诊断
治疗
Infantile spasms
Clinical diagnosis
Treatment
