手足口病复治86例分析

Analysis of 86 cases of the retreatment about hand foot and mouth disease

目的:探讨复治手足口病临床特征及病原学感染情况。方法:收治手足口病复治患者86例,作为复治组,初治组86例和对照组手足口病90例。观察各组EV71感染情况,并对早期重症临床指标及预后进行对比分析。结果:复治组EV71(+)52例,随访结果,病程第1周EV71阴转0例,第2周阴转10例,阴转率19.23%。结论:复治手足口病存在复发、重复感染及交叉感染等多种感染途径,EV71(+)者为主要传染源,对EV71感染手足口病患儿应隔离至3~4周以防传播。

Objective:To investigate the clinical features and pathogen infection of hand foot and mouth disease.Methods:86patients with hand foot and mouth disease with retreatment were selected as the retreatment group.Initial treatment group had 86patients,the control group had 90 patients.Infection of EV71 of the three groups was observed,the clinical index about the early stage of severe and prognosis were compared.Results:In the retreatment group,52 cases were EV71(+);after follow-up,EV71 of 0case was negative at the first week,EV71 of 10 case were negative at the second week,negative conversion rate was 19.23%.Conclusion:Retreatment of hand foot and mouth disease has many kinds of infection,such as recurrent,repeated infection and cross infection and so on.EV71(+) is the main source of infection.Children with hand foot and mouth disease with EV71 infection should be isolated for 3 to 4 weeks to prevent the spread.