类风湿膝关节炎高频彩色多普勒超声表现及其与实验室检查的相关性

Correlation between manifestations of high frequency color doppler ultrasound and laboratory examination of knee joints lesions in patients with rheumatoid arthritis

目的:探讨类风湿膝关节炎高频彩色多普勒超声表现与实验室检查的相关性。方法:对40例类风湿患者58个病变膝关节与30例正常人30个正常膝关节行高频彩色多普勒超声检查。观察内容:髌上囊积液、滑膜及其内血供、股骨下端关节软骨及骨皮质变化、有无腘窝囊肿形成等。分析滑膜厚度及髌上囊积液深度与血沉及C反应蛋白的相关性。结果:类风湿患者膝关节出现不同程度滑膜增厚,髌上囊积液增多。采用Spearman相关分析,髌上囊积液深度与血沉相关系数0.306,P<0.05,与C反应蛋白相关系数0.293,P<0.05;滑膜厚度与ESR及CRP均未见明确相关性。结论:高频超声可以清晰显示类风湿关节炎膝关节病变,其与实验室检查有一定相关性,可在一定程度上为诊断类风湿提供依据。

Objective:To explore the correlation between manifestations of high frequency color Doppler ultrasound and laboratory examination of knee joints lesions in patients with rheumatoid arthritis(RA).Methods:40 patients of 58 knee joints with rheumatoid arthritis and 30 health adults of 30 knee joints were checked.We observed suprapatellar pouch effusion,synovial membrane and its blood supply,distal femoral articular cartilage and cortical bone changes,with or without popliteal cyst and so on.We analyzed the correlation among the synovial thickness,suprapatellar pouch effusion,erythrocyte sedimantation rate(ESR) and C-reactive protein(CRP).Results:There were different degrees of synovial thickness and suprapatellar pouch effusion in knee joints of patients with RA.By using Spearman analysis,the correlation coefficient was 0.306(P<0.05) between the degree of suprapatellar pouch effusion and erythrocyte sedimantation rate,the correlation coefficient was 0.293(P<0.05) between the degree of suprapatellar pouch effusion and C-reactive protein.Conclusion:The high frequency ultrasound can clearly show the knee joints disease of rheumatoid arthritis,there is a certain relationship between it and laboratory examination,and it can provide the basis for the diagnosis of rheumatoid arthritis in a certain extent.