小儿支原体肺炎95例临床观察

Clinical observation of 95 cases of children with mycoplasma pneumonia

目的:探讨红霉素、阿奇霉素治疗小儿支原体肺炎的临床效果。方法:2012年2月-2014年1月收治支原体肺炎患儿95例,对照组40例给予红霉素30mg/(kg·日)溶于50g/L葡萄糖中静滴,1次/日,连续治疗14天;观察组50例在对照组的基础上加用阿奇霉素10mg/(kg·日)溶于50g/L葡萄糖中静滴,1次/日,连用5天。结果:观察组55例患儿治愈50例,治愈率90.1%,显效3例,进步2例,总有效率100.0%;对照组40例患儿治愈24例,治愈率60.5%,显效6例,进步5例,无效5例,总有效率87.5%,两组比较差异有统计学意义(P<0.05)。结论:红霉素联合阿奇霉素是治疗小儿支原体肺炎的有效药物组合,值得临床推广。

Objective:To investigate the clinical effect of erythromycin and azithromycin in the treatment of children with mycoplasma pneumonia.Methods:95 children with mycoplasma pneumonia were selected from February 2012 to January 2014.40 cases of the control group were treated with erythromycin 30 mg /(kg·day) dissolved in 50g/L glucose intravenously,1 time/day,continuous treatment for 14 days.Based on the treatment of the control group,50 cases of the observation group were treated with azithromycin 10mg/(kg·day)dissolved in 50g/L glucose intravenously,1 time/day,continuous treatment for 5 days.Results:In 55 cases of the observation group,50 cases were cured,the cure rate was 90.1%.3 cases was effective,2 cases was progress.The total efficiency was 100.0%.In 40 cases of the control group,24 cases were cured,the cure rate was 60.5%.6 cases was effective,5 cases was progress,5 cases was no effective.The total efficiency was 87.5%.There were significant differences between those of two groups(P<0.05).Conclusion:Erythromycin combined with azithromycin is the effective drug in the treatment of children with mycoplasma pneumonia,it is worthy of promotion.