急性一氧化碳中毒导致心肌损伤的临床观察

Clinical observation of acute carbon monoxide poisoning cause myocardial damage

目的:探讨不同程度急性一氧化碳中毒(ACMP)对心肌损伤的结果。方法:2006年1月-2012年12月收治ACMP患者168例,按中毒程度分为轻、中重度两组,其中轻度78例,中重度90例。所有患者均给予心电图、心肌酶谱(CK和CK-MB)及心肌钙蛋白(CTnI)监测,以评价对心肌的损害程度。结果:轻度中毒患者心电图异常3例(3.8%),CTnI,CK及CK-MB升高1例(1.1%),中重度患者心电图异常72例(79%),CTnI,CK和CK-MB升高24例(35.3%)。结论:中重度急性一氧化碳中毒可导致心肌损害。

Objective:To discuss the result of inordinately acute carbon monoxide poisoning(ACMP)to myocardial damage. Methods:To admit 168 cases of patients with ACMP from January 2006 to December 2012,according to the degree of poisoning, they were divided into mild group,moderate and severe group, mild group in 78 cases,moderate and severe group in 90 cases.All patients were given ECG,myocardial enzymes(CK and CK-MB)and cardiac troponin I(CTnI)monitoring,to evaluation of myocardial damage.Results: Abnormal ECG of mild group was 3 cases(3.8%),CTnI,CK and CK-MB increased was 1 case(1.1%). Abnormal ECG of moderate and severe group was 72 cases(79%),CTnI,CK and CK-MB increased was 24 cases(35.3%). Conclusion:Moderate and severe cute carbon monoxide poisoning can cause myocardial damage.