呼吸道感染患者病原性细菌的检验临床观察

Clinical observation of the examination of pathogenic bacteria in patients with respiratory tract infections

目的:分析呼吸道感染患者病原性细菌的分类及耐药性。方法:2012年8月-2013年12月收治呼吸道感染患者80例,将痰液标本进行分离、培养、鉴定,细菌采用K-B纸片法测定药敏性,真菌采用真菌药敏条进行鉴定。结果:本组80例患者共分离出菌株112株,其中革兰阳性菌58株(51.79%),革兰阴性菌47株(41.96%),真菌7株(6.25%),最常见的感染菌为金黄色葡萄球菌、铜绿假单胞菌及肺炎链球菌。革兰阳性菌主要对青霉素耐药,革兰阴性菌主要对氨苄西林、头孢曲松耐药。结论:呼吸道感染菌主要为革兰阳性菌,多重耐药现象普遍,临床上应加强抗菌药物管理、合理用药,以缓解目前临床上多重耐药性的危机。

Objective:To analyze the classification and drug resistance of pathogenic bacteria in respiratory tract infection patients.Methods:We separated,cultivated,appraised the sputum specimen of 80 cases with respiratory tract infection from August2012 to December 2013 who were selected.The drug sensitivity was tested by K-B method in bacterial,and fungi were identified with fungal susceptibility.Results:112 pathogens were isolated in 80 cases,including 58 gram positive strains(51.79%),47 strains gram negative bacteria(41.96%),7 strains fungi(6.25%).The most common infection bacteria were staphylococcus aureus,pseudomonas aeruginosa and streptococcus pneumoniae.The gram positive bacteria was resistant to penicillin,and the gram negative bacteria was resistant to ampicillin and ceftriaxone.Conclusion:The major respiratory tract infection bacteria was gram positive bacteria,and the multi-drug resistance is widespread.We should strengthen the management of antimicrobial agents and the rational use of drugs,in order to alleviate the current crisis clinical multidrug resistance in Clinical.