摘要
目的:探讨婴幼儿维生素D缺乏性佝偻病的防治方法,即在服用维生素D3400IU基础上,是否需同时添加钙剂。方法:将120例足月出生的健康婴儿随机分为观察组(单纯添加维生素D3)和对照组(添加维生素D3和钙剂),随访两组婴儿至6个月,观察其生长发育情况、佝偻病患病情况以及6个月时血清25-羟维生素D[25-(OH)D]及血钙水平。结果:两组婴儿在发育指标、佝偻病患病率、血清25-(OH)D及血钙水平上的差异均无统计学意义(P>0.05)。结论:对于足月出生的健康新生儿,在婴儿期只要保证摄入维生素D3400IU,即能达到预防佝偻病的目的,无需额外补充钙剂。
Objective:To investigate the prevention and treatment methods for the infants with vitamin D deficiency rickets,whether to add calcium when took Vitamin D3400IU.Methods:120 healthy infants born at term were randomly divided into the observation group(simple add Vitamin D3) and the control group(add Vitamin D3and calcium).We followed them for 6 months to observe the growth and development situation,the prevalence of rickets and the serum 25-hydroxyvitamin D[25-(OH)D] and serum calcium levels at 6 months. Results: There were no significant differences in the development index,the prevalence of rickets,the 25-(OH)D and serum calcium levels of the two groups(P>0.05).Conclusion:For the full-term born healthy neonates,if we guarantee the intake of Vitamin D3400IU in infancy,which can reach the purpose of preventing rickets,so we need not add the calcium.
