摘要
目的:讨论吸入性药物在妊娠期支气管哮喘轻中度急性发作中的临床治疗效果。方法:将45例支气管哮喘孕妇随机分为三组:沙丁组、沙异组、沙布组,每组15例,沙丁组给予沙丁胺醇雾化吸入,另两组在沙丁组基础上分别加用异丙托溴胺、布地奈德吸入剂。结果:沙丁组与沙异组、沙布组治疗后各指标比较,差异有统计学意义(P<0.05);沙异组与沙布组治疗后比较,差异无统计学意义(P>0.05)。结论:妊娠合并支气管哮喘轻中度急性发作时,吸入β2受体激动剂加抗胆碱药物能有效缓解气道的痉挛,减少炎性细胞介质的释放,从而改善患者临床症状。
Objective:To discuss the clinical therapeutic effect of inhaled drugs in pregnancy bronchial asthma.Methods:45 cases of bronchial asthma in pregnant women were randomly divided into 3 groups:Salbutamol group,salbutamol+ipratropium bromide group,salbutamol+budesonide group,15 cases in each group.The salbutamol group were given salbutamol,and the other two groups were given ipratropium bromide and budesonide inhalation respectively based on the salbutamol group.Results:We compared the index of 3 groups after the treatment,and there was statistically significant(P<0.05).We compared the salbutamol + ipratropium bromide group and the salbutamol+budesonide group,and there was no significant difference(P>0.05).Conclusion:The pregnancy complicated with bronchial asthma,the inhalation of β2 receptor agonist and anticholinergic drugs can relieve airway spasm and reduce inflammatory mediator release,so it can improve the clinical symptoms of patients.
