2013年我院药品不良反应报告分析

Analysis of reports of drug's adverse reaction in our hospital in 2013

目的:对上报的ADR报告进行分类统计、分析,为临床合理用药及药物安全性评价提供依据。方法:采用回顾性分析对2013年上报的46份ADR报告,按患者年龄、性别、给药途径、引发ADR的药品种类、涉及器官或系统以及临床表现等进行统计、分析。结果:≥60岁的老年人是ADR的高发人群,所占比例达45.65%;静脉给药较其他途径给药更易发生ADR(82.61%);中药注射剂引起的ADR比例最高(32.60%),其次为抗菌药物(26.08%);46例ADR报告中,以皮肤及附件损害最常见,其次为神经系统。结论:加强药品不良反应监测工作,可以提高医务人员对药品不良反应监测的意识,减少或避免药品不良反应的重复发生。

Objective:We analyzed and classified statistics the report of ADR which be reported,in order to provide the basis fthe drug safety evaluation and clinical rational drug use.Methods:We retrospective analyzed the 46 ADR cases reported in 201 according to the patient's age,gender,route of administration,raises the ADR drugs,organs and systems involved and clinicmanifestations.Results:60 years old(including 60 years old) of the elderly are at high risk of ADR,accounted for 45.65% Intravenous drug are more prone to ADR than other routes of administration(82.61%).The traditional Chinese medicine injecticaused the highest percentage of ADR(32.60%),followed by antibiotics(26.08%).In 46 cases of ADR reports,the lesion of skin aits appendages are the most common,followed by the nervous system.Conclusion:If we strengthened the ADR monitoring,it cimprove the medical staff awareness of the adverse drug reaction monitoring,and reduce or avoid adverse drug reactions happen repeatedly.