摘要
目的:探讨泮托拉唑联合阿莫西林、痢特灵治疗幽门螺杆菌阳性消化性溃疡的疗效。方法:选择幽门螺杆菌阳性的消化性溃疡患者92例,随机分为观察组和对照组各46例,观察组予口服泮托拉唑肠溶片40 mg,1次/日,阿莫西林1.0 g,2次/日,痢特灵0.1 g,3次/日;对照组予口服泮托拉唑肠溶片40 mg,1次/日,阿莫西林1.0 g,2次/日,甲硝唑0.4 g,3次/日;疗程2周。结果:观察组幽门螺杆菌根除率及总有效率高于对照组,差异有统计学意义(P<0.05)。结论:泮托拉唑联合阿莫西林、痢特灵治疗幽门螺杆菌阳性消化性溃疡疗效显著,性价比适中,患者依从性高,适合在门诊应用。
Objective:To investigate the efficacy of pantoprazole combined with amoxicillin and furazolidone in the treatment of helicobacter pylori positive peptic ulcer.Methods:92 cases with peptic ulcer and the elicobacter pylori positive were selected.They were randomly divided into the observation group and the control group with 46 cases in each.The observation group received oral pantoprazole enteric-coated tablets 40 mg,1 time/day,amoxicillin 1.0 g,2 times/day,furazolidone 0.1 g,3 times/day.The control group received oral pantoprazole enteric-coated tablets 40 mg,1 time/day, amoxicillin 1.0 g,2 times/day,metronidazole 0.4 g,3times/day.They were treated for 2 weeks.Results:The helicobacter pylori eradication rate and total efficiency of the observation group were higher than that of the control group.There was significant difference(P<0.05).Conclusion:The efficacy of pantoprazole combine with amoxicillin and furazolidone in the treatment of helicobacter pylori positive peptic ulcer is significantly.Its price is moderate,and high patient compliance.So it is suitable for application in clinic.
