摘要
目的:探讨分析埃索美拉唑和奥美拉唑在治疗胃溃疡疾病的临床效果。方法:2008年3月-2010年2月收治幽门螺旋杆菌阳性胃溃疡患者175例,回顾性分析其临床资料,并将这些患者在各自的意愿下随机分成埃索美拉唑组86例和奥美拉唑组89例。埃索美拉唑组和奥美拉唑组均在应用克拉霉素和阿莫西林的基础上,再分别应用埃索美拉唑和奥美拉唑进行治疗。结果:奥美拉唑组的临床疗效明显低于埃索美拉唑组,差异有统计学意义(P<0.05)。结论:埃索美拉唑治疗胃溃疡总有效率比较理想,且不良反应少,是安全有效的首选药物。
Objective:To explore and analyze the clinical effect of esomeprazole and omeprazole in the treatment of gastric ulcer disease.Methods:175 gastric ulcer patients with helicobacter pylori positive were selected from March 2008 to February 2010.The clinical data were retrospectively analyzed.They were randomLy divided into the esomeprazole group with 86 cases and the omeprazole group with 89 cases under their own will.The esomeprazole group and the omeprazole group were respectively treated with esomeprazole and omeprazole on the basis of the application of clarithromycin and amoxicillin.Results:The clinical efficacy of the omeprazole group was significantly lower than that of the esomeprazole group,and the difference had statistical significance(P0.05).Conclusion:The total effective rate of esomeprazole in the treatment of gastric ulcer is ideal.It has less adverse reactions.It is the safe and useful preferred drug for treatment.
