亚临床甲减的早期干预在妊娠期妇女中的临床价值

Constructe the ideas of clinical value for early intervention in pregnant women with subclinical hypothyroidism

目的:探讨亚临床甲减的早期干预在妊娠期妇女中的临床应用价值。方法:回顾性分析本院2011年10月-2013年10月收治的亚临床甲减妊娠期妇女的临床资料,所有患者随机分成早期干预组和非干预组,探讨早期干预在亚临床甲减妊娠期妇女中的应用价值。结果:干预组孕妇妊高征、剖宫产、羊水过多、早产、巨大胎儿、胎儿畸形、呼吸窘迫、死胎死产的发生率分别为9.80%、78.43%、9.80%、15.69%、7.84%、9.80%、5.88%、1.96%,与非干预组的39.21%、92.1%、35.29%、52.94%、25.49%、27.45%、19.61%、11.76%相比差异具有统计学意义(P<0.05)。结论:早期干预能显著改善亚临床甲减妊娠期妇女甲状腺功能,同时改善妊娠孕妇和胎儿的预后,值得临床推广使用。

Objective:To investigate the clinical application value of early intervention on pregnant women with subclinical hypothyroidism.Methods:Pregnant women with subclinical hypothyroidism were selected from October 2011 to October 2013.We analyzed their clinical data retrospectively.All cases were randomLy divided into the early intervention group and the non intervention group,to explore the value of application early intervention in pregnancy women with subclinical hypothyroidism.Results:Pregnancy induced hypertension syndrome,cesarean delivery,polyhydramnios,fetal macrosomia,premature delivery,fetal malformation,respiratory distress,stillbirth incidence rates of pregnant women in the intervention group were 9.80%,78.43%,9.80%,15.69%,7.84%,9.80%,5.88%,1.96%,when compared with 39.21%,92.1%,35.29%,52.94%,25.49%,27.45%,19.61%,11.76% of the non diabetes group,the difference were statistically significant(P0.05).Conclusion:Early intervention can significantly improve the subclinical hypothyroidism thyroid function in pregnancy,and also can improve the prognosis of maternal and fetal pregnancy,so it is worthy of clinical application.