亚低温治疗急性脑出血的临床疗效观察

Observation of the clinical effect of mild hypothermia on acute cerebral hemorrhage

目的:探讨亚低温治疗急性脑出血的临床疗效。方法:2010年2月-2014年2月收治急性脑出血患者112例,按入院顺序分为观察组和对照组,各56例。两组均给予常规药物治疗,观察组在此基础上采用亚低温联合治疗。对比治疗后两组临床症状改善情况、格拉斯昏迷程度评分(GCS)、神经功能缺损程度评分(ESS)。结果:治疗后两组症状均有所改善,但观察组较对照组改善明显,差异有统计学意义(P<0.05);治疗前两组GCS、ESS评分无显著差异,治疗30 d后观察组评分均优于对照组,差异有统计学意义(P<0.05)。结论:亚低温治疗较常规药物治疗能有效改善急性脑出血患者的临床症状,有效缓解患者昏迷及神经功能损伤,减少意识障碍持续时间,提高出院后生活能力。

Objective:To explore the clinical effect of mild hypothermia on acute cerebral hemorrhage.Methods:112 cases with acute cerebral hemorrhage were selected from February 2010 to February 2014.They were divided into the observation group and the control group with 56 cases in each group according to the order of admission.The two groups were given routine therapy,and the observation group were treated with mild hypothermia therapy on the basis of that.We compared the improvement of clinical symptoms,glass coma score(GCS),neural function defect score(ESS) after treatment of the two groups.Results:After treatment,symptoms of two groups were improved,but the observation group was better than the control group.The difference was statistically significant(P0.05).Before treatment,there was no significant difference between two groups in GCS,ESS score.30 days after treatment,the observation group was superior to the control group,and the difference was statistically significant(P0.05).Conclusion:Compared with conventional drug therapy,mild hypothermia therapy can effectively improve the clinical symptoms in patients with acute cerebral hemorrhage,relieve the coma and nerve function injury,reduce the duration of disturbance of consciousness,and improve the ability of life.