急诊应用胺碘酮治疗冠心病快速心律失常100例的临床效果观察

Clinical effect observation of emergency application of amiodarone in 100 cases of coronary heart disease rapid arrhythmia

目的:探讨冠心病快速心律失常急诊应用胺碘酮治疗的具体应用概况和临床效果。方法:2012年12月-2013年12月收治冠心病快速心律失常患者100例,作为研究对象,对所有患者的临床资料进行回顾性分析,并给予所有患者胺碘酮治疗。总结胺碘酮治疗所取得的临床疗效和具有的临床价值。结果:100例冠心病快速心律失常患者采用胺碘酮治疗后室性早搏患者和阵发性房颤患者的转复率分别为92.3%和96.6%。这两种心律失常疾病应用胺碘酮治疗后其转复率较其他类型心律失常的转复率高出很多,转复率相比较差异有统计学意义(P<0.05)。在治疗过程中有7例患者出现不良反应,不良反应主要是以血压下降幅度过大为主(5例),即血压下降至90/60 mmHg。这种不良反应在通过加快输液速度、适当补充血容量后均能够纠正。另外2例在心律恢复后有恶心呕吐症状,但在调节滴速度等后较快恢复。结论:胺碘酮在冠心病快速心律失常急诊治疗上应用能够取得较为显著的临床疗效,值得推广。

Objective:To explore the specific application and clinical effect of emergency application of amiodarone in the treatment of coronary heart disease rapid arrhythmia.Methods:100 cases with coronary heart disease rapid arrhythmia were selected as the research objects from December 2012 to December 2013.The clinical data of all patients were retrospectively analyzed,and all patients were treated with amiodarone.The clinical curative effect and clinical value of amiodarone treatment were summarized.Results:100 cases with coronary heart disease rapid arrhythmia were treated with amiodarone.The cardioversion rates of patients with ventricular premature beat and patients with paroxysmal atrial fibrillation were respectively 92.3% and96.6%.After this two kinds of arrhythmia diseases were treated with amiodarone,the cardioversion rates were much higher than the cardioversion rates of other types of arrhythmias.The cardioversion rates had significant difference with statistical significance(P<0.05).In the treatment process,7 cases had adverse reactions.The adverse reaction was mainly by too large blood pressure drop(5cases),and it was that the blood pressure dropped to 90/60 mm Hg.The adverse reaction could be corrected by speeding up the infusion and appropriate supplement blood volume.Other 2 cases had nausea and vomiting symptoms after the heart rate recovery,but it was faster recovery after adjusting the drip speed.Conclusion:Amiodarone in the emergency treatment of coronary heart disease rapid arrhythmia can achieve more significant clinical curative effect.It is worthy of promotion.