新生儿缺氧缺血性脑病68例临床分析

Clinical analysis of 68 cases of neonatal hypoxic ischemic encephalopathy

目的:探讨新生儿缺氧缺血性脑病的治疗方法及临床效果。方法:2012年3月-2014年2月收治新生儿缺氧缺血性脑病患儿68例,在常规治疗基础上在生后2~3 d后给予静滴单唾液酸神经节苷酯10~14 d。观察疗效并进行临床分析。结果:68例新生儿缺氧缺血性脑病患儿经治疗10~14 d后NBNA评分均明显升高,神经系统症状明显改善。结论:采用单唾液酸神经节苷酯注射液治疗新生儿缺氧缺血性脑病,能快速修复损伤后的神经细胞,疗效显著。

Objective:To investigate the treatment method and clinical effect of neonatal hypoxic ischemic encephalopathy.Methods: 68 cases of hypoxic ischemic encephalopathy were selected from March 2012 to February 2014.In 2~3 days after birth,we gave them with single sialic acid ganglioside intravenous drip for 10~14 days on the basis of the routine treatment.We observed and analyzed the clinical effect.Results: After 10 to 14 days treatment, NBNA scores of 68 cases of neonatal hypoxic ischemic encephalopathy children were significantly elevated,and the nervous system symptoms improved significantly.Conclusion:The single sialic acid ganglioside injection in the treatment of neonatal hypoxic ischemic encephalopathy can repair the injured neurons,and the curative effect is significant.