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CCB与ARB联合治疗青年原发性高血压的临床效果分析 被引量:2

Analysis of the clinical effect of CCB and ARB in the treatment of young patients with primary hypertension
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摘要 目的:探讨CCB与ARB联合治疗青年原发性高血压的效果。方法:2011年1月-2014年1月收治青年原发性高血压患者180例,按照入院编号随机分为3组,各60例,A组采用硝苯地平控释片(CCB)治疗;B组采用厄贝沙坦(ARB)治疗;C组采用联合治疗法。治疗2周后,比较患者的尿蛋白改善情况。结果:C组患者尿蛋白含量明显下降,血压得到有效的控制;且C组患者在接受联合治疗后,5例发生不良反应,而A组和B组的例数分别为42例和57例,其不良反应发生情况明显高于C组,组间治疗效果比较差异有统计学意义(P<0.05)。结论:临床上在治疗青年原发性高血压疾病时,可以采用CCB与ARB联合治疗方法,能有效改善患者尿蛋白含量,改善患者生活质量,获得非常理想的治疗效果,值得在临床上大力推广。 Objective:To explore the clinical effect of CCB and ARB in the treatment of young patients with primary hypertension.Methods:180 young patients with essential hypertension were selected from January 2011 to January 2014.They were divided randomly into three groups with 60 patients in each according to the admission number.A group was treated with nifedipine GITS(CCB);B group was treated with irbesartan(ARB);C group was treated with combined therapy.2 weeks after the treatment,we compared the improvement of urinary protein.Results:In the C group,urinary protein content was significantly decreased,and blood pressure can be controlled effectively.In the C group,the total number with adverse reaction were 5 cases,and in the A group and B group,this number was respectively 42 cases and 57 cases;the incidence of adverse reactions was significantly higher than that in C group.We compared the effect among the three groups,the difference was statistically significant(P<0.05).Conclusion:Clinically,when we treat youth primary hypertension disease,we can use CCB and ARB combined therapy.It can effectively improve the content of urinary protein of patients,improve the quality of life of patients,and obtain ideal curative effect.It is worth popularizing in clinic.
作者 荣子胜
出处 《中国社区医师(医学专业)》 2014年第28期22-23,共2页
关键词 青年原发性高血压 硝苯地平控释片 厄贝沙坦 尿蛋白 Youth primary hypertension Nifedipine controlled release tablets Irbesartan Urinary protein
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