西咪替丁联合双嘧达莫治疗小儿秋季腹泻96例疗效观察

Curative effect observation of cimetidine and dipyridamole in treatment of 96 cases of infantile autumn diarrhea

目的:探究采用西咪替丁联合双嘧达莫治疗小儿秋季腹泻的临床疗效。方法:2013年2月-2014年2月收治秋季腹泻患儿96例,随机分为试验组和对照组,各48例,试验组采用西咪替丁联合双嘧达莫治疗。对照组服用双嘧达莫治疗,对比两组的治疗效果。结果:试验组治疗后显效33例,有效14例,无效1例,总有效率97.92%;对照组治疗后显效23例,有效12例,无效13例,总有效率72.92%;试验组的治疗效果明显优于对照组,差异有统计学意义(P<0.05)。试验组治疗时间(2.2±1.2)d,止泻时间(0.5±0.3)d;对照组治疗时间(4.3±1.0)d,止泻时间(1.3±0.6)d;试验组在治疗时间、止泻时间均明显短于对照组,差异有统计学意义(P<0.05)。讨论:采用西咪替丁联合双嘧达莫治疗小儿秋季腹泻效果显著,可以缩短患儿的治疗时间和止泻时间。

Objective:To explore the curative effect of cimetidine and dipyridamole in treatment of 96 cases of infantile autumn diarrhea.Methods:96 children with autumn diarrhea were selected from February 2013 to February 2014.They were randomly divided into the experimental group and the control group with 48 cases in each.The experimental group were treated with cimetidine and dipyridamole.The control group were treated with dipyridamole.We compared the treatment effect of two groups.Results:In the experimental group,33 cases were markedly effective;14 cases were effective;1 case was invalid;total effective rate was 97.92%.In the control group,23 cases were markedly effective;12 cases were effective;13 cases were invalid;total effective rate was 72.92%.The efficacy of the experimental group was significantly better than the control group,and the difference was statistically significant(P<0.05).In the experimental group,the treatment time was(2.2±1.2) days;antidiarrheal time was(0.5±0.3) days.In the control group,the treatment time was(4.3±1) days;antidiarrheal time was(1.3±0.6) days.The treatment time and the antidiarrheal time in the experimental group were significantly shorter than those of the control group,and the difference was statistically significant(P<0.05).Conclusion:The curative effect of cimetidine and dipyridamole in treatment of infantile autumn diarrhea is significant.It can shorten the treatment time and antidiarrheal time.